By Kai-Uwe Lewandrowski
Advances in Spinal Fusion finds a brand new iteration of fabrics and units for more advantageous operations in spinal fusion. This reference showcases rising learn and applied sciences in parts reminiscent of biodegradable implants, drug supply, stem telephone isolation and transfection, phone encapsulation and immobilization, and the layout of second and 3D scaffolds for cells. It captures a cascade of suggestions an important to elevated therapeutic and lowered morbidity in spinal fusion equipment and mechanics and addresses present criteria in analytical method and qc, it describes the choice of biomaterials for better biocompatibility, biostability, and structure/function relationships.
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Extra info for Advances in spinal fusion : molecular science, biomechanics, and clinical management
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The spinal cord appears to be at little risk of thermal injury as long as the cement is properly injected and contained within the VB. If cement were to leak into the spinal canal and come into direct contact with the cord, it is not unrealistic to expect that thermal injury might occur. © 2004 by Marcel Dekker, Inc. B. Cytotoxicity The methylmethacrylate (MMA) monomer component of PMMA cement is cytotoxic and therefore has been implicated as a mechanism of pain relief . Cell cultures show that MMA monomer is toxic to leukocytes and endothelial cells when concentrations exceed 10 mg/mL , but its effect on neural tissue remains unknown.