Advances in Hemodynamics and Hemorheology by T.V. How

By T.V. How

This sequence provides experiences overlaying all facets of haemodynamics and haemorheology. themes lined contain the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood movement in arteries and veins. The contributions goal to mirror the advances being made in experimental suggestions and instrumentation for laboratory and medical measurements and in numerical and mathematical modelling. Emphasis is put on the medical and engineering ideas concerned, yet specific realization is usually given to the scientific value of this zone of study. issues lined by way of this quantity comprise viscoelastic houses of blood and blood analogues; blood move via slim tubes; and numerical modelling of blood movement.

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It is then found, that under the influence of the viscous forces due to theflovv^,all cells take similar prolate ellipsoidal shapes oriented with respect to the streamlines. The deformation D of the cell in the shear plane, is defined as: D = (L-B)/(L + B), where L and B denote respectively the length and the breadth of the deformed particle. The experiments show that deformation increases with the external shear stress and also depends on the viscosity ratio X between the hemoglobin solution and the suspending liquid (Figure 6).

Shear rate dependent viscoelastic character very similar to blood has been found using solutions of water soluble polymers. These are usable for modeling blood Viscoelasticity of Blood 21 flow in uniform channels with cross sections which are large compared to the granularity of blood. ^^ Also, no information is available on expected differences in extensional properties of blood compared with polymers. Differences may be due to the layered character of the flow induced microstructure in blood as compared to more rapidly responding entanglements with polymer chains.

Effect of procaine hydrochloride on the aggregation behavior and suspension viscoelasticity of human red blood cells. Biorheology 1989, 25,951-972. 52. ; Lee, M. Studies of fluids simulating blood-like rheological properties and applications in models of arterial branches. Biorheology 1991,28, 39-52. 53. ; Friis-Baastad, L. Blood modeling using polystyrene microspheres. Biorheology 1989,25,401—413. 54. M. Flow of non-Newtonian blood analog fluids in rigid curved and straight artery models. Biorheology 1990, 27, 711-733.

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